INVESTIGATE NANOPARTICLE SIZE DISTRIBUTIONS AND CONCENTRATION OVER TIME IN THE LAB

The BRAVE B2 nanoparticle analyzer gives you a second-by-second, particle-by-particle view of your particles and nanoparticles, and even detects ultra-low concentrations and uncommon large particles. 

You benefit from: 

  • Insight into sample behavior over time, e.g. from one second to several hours

  • Single-particle accuracy, similar to NTA but with ultra-high particle count and results in seconds, updated continuously

  • Information on aggregration, dissociation, large particle counts and monitoring of rare oversized particles

  • In-depth knowledge of different particle populations, including ultra-low concentrations, oversized particles and anomalies.

BRAVE B2 was presented at Analytica 2022 in Munich and will be launched in Q1 2023.

Here you see time-resolved PSD: Particle formation processes during liquid-liquid phase separation (LLPS) with low (left) and high (right) RNA concentrations.  

BRAVE B2: 
A MODULAR PLATFORM

BRAVE B2 - Choose your insights

BRAVE B2 is made up of different modules. Choose what you want to determine. You can add more modules to your BRAVE B2 at any time later.

Concentration determination

Detection of ultra-low concentrations, e.g. nanoplastics, water for injections.

Time-resolved sizing

Monitoring particle size distributions continously, directly out of containers. 

Sizing range: 20 nm to 3 µm (sample-dependent)

Low-volume sizing

Determination of particle size distribution from low volumes, starting at 20 µl (sample-dependent).

Sizing range extension

Detection of large particle tails, LPC, aggregation behaviors.

Sizing range: 20 nm to 50 µm (sample-dependent)

Coming soon: particle analysis

Characterizing particle populations using spectroscopic particle data. 

Coming soon: Raman tweezers

Characterization on a single-particle basis with Raman spectroscopy. 

 

SPECIFICATIONS

  • Continuous, time-resolved sample scans on up to 4K particles per minute

  • Measuring statistics as number-based hydrodynamic size distribution

  • Particle sizing range: 
    20 nm to 50 µm
    (module-dependent)

  • For nanosuspensions, nanoemulsions and colloidal formulations (liquid continuous phase; solid or liquid dispersed phase)

SOFTWARE

BRAVE B2 is delivered with the H.A.N.S. software. H.A.N.S. stands for High-throughput Analysis Nano-characterization Software; it is an integrated data management system for managing, transferring and storing your measurement data. H.A.N.S. also connects BRAVE B2 with your LIMS to enable simple further processing of the data. Special interfaces are available on request.

 

 

TALK TO US

Are you ready to talk our experts? 

We look forward to getting your message and will respond via email or telephone call, whichever suits you best. We also offer an online or on-site demo and test measurements on your samples.